RIO DE JANEIRO—Study results indicate a positive association between the type of treatment modality chronic kidney disease (CKD) patients receive and the likelihood for them having periodontitis, reported MedWire News.
Specifically, CKD patients undergoing predialysis or hemodialysis are significantly more likely to have severe chronic periodontitis than their counterparts treated with continuous ambulatory periodontal dialysis (CAPD) or healthy individuals without CKD.
"The pathogenesis of periodontitis elicits the production of cytokines, prostaglandins, and in some cases, acute phase reagents, such as C-reactive protein; therefore periodontitis may have a systemic negative effect on homeostasis and a negative influence on any ongoing disease," explain Ricardo Fischer and colleagues from Rio de Janeiro State University, Brazil.
Their study included 40 CAPD patients, 40 hemodialysis patients, 51 predialysis patients, and 67 healthy individuals with no clinical signs of ongoing systemic disease.
All study participants underwent oral clinical examinations, and chronic periodontitis was defined as having clinical attachment loss of at least 4 mm in more than 30 percent of oral sites, while severe chronic periodontitis denoted the presence of at least four sites with clinical attachment loss of at least 6 mm.